布莉Grillo-Hill
Assistant Professor 布莉Grillo-Hill and Harnoor Virk, ’21 Molecular Biology and minor in Chemistry, examine slides of whole mount dissected fly tissues expressing fluorescent proteins that indicate whether cells are actively dividing using an inverted live-cell imaging microscope that they built from comp一个nts at 菠菜网lol正规平台.
Impacts of intracellular pH on cancer 细胞行为
布莉Grillo-Hill’s research characterizes and identifies pH sensors that mediate cancer 细胞行为. She has designed tools that measure and alter acid levels inside cells – a first in the field development – which allow her to better understand diseases 以及他们是如何进步的.
“Cells generate acids as a normal consequence of metabolism and other biochemical 活动，”她解释道. “In diseases including cancer, cells cannot properly regulate their acid levels, and acid levels are subsequently reduced. 这反过来又会产生蛋白质 to function abnormally, which makes the cells behave differently, contributing to 疾病进展.”
Grillo-Hill’s students are active in her lab and fully engaged in research. 事实上, they have presented their research at the Society for Advancement of Chicanos/Hispanics and Native Americans in 科学 Conference, the Annual Drosophila Research Conference, the California State University Annual Biotechnology Symposium, and the Annual Biomedical Research Conference for Minority Students.
Several of Grillo-Hill’s students have g一个 on to pursue graduate and medical degrees, including at top-ranked programs like UC San Francisco. 其他人也采取了立场 at Takeda Pharmaceuticals, Beckman Coulter, and at the California Department of Justice Jan Bashinski DNA Laboratory, as well as in academic labs at UC San Francisco and the University of Pennsylvania.
Grillo-Hill considers her students’ hands-on research experiences successful, “even if they don’t continue to work as a bench scientist,” she says. 他们学会了合作 and critical thinking skills in research that will benefit them in whatever path they 毕业后选择.”
"指导 and mentorship from my professor have opened career doors that I would never 我知道."
Harnoor Virk
’21 Molecular Biology and minor in Chemistry
菠菜网lol正规平台 研究基金会 2020 年度报告
